At Platte Hemp Company, we’re all about digging into the facts behind the plant—and today, we’re spotlighting a cannabinoid that’s gaining attention for its relaxing effects: CBN (Cannabinol). Often overshadowed by CBD and THC, CBN is emerging as a unique compound with special benefits, especially for sleep and pain.

Table of Contents

What is Kratom?

Kratom (Mitragyna speciosa) is a tree native to Southeast Asia. For centuries, its leaves have been used as a natural remedy for energy, pain, and mood support. Today, kratom is gaining attention as a plant with real potential—especially thanks to two of its main active compounds:

Mitragynine – the most abundant alkaloid in kratom.
7-Hydroxymitragynine (7-OH) – a much smaller compound by volume, but significantly more potent.
Your body naturally converts mitragynine into 7-OH after consumption, which is where kratom gets its strongest effects.

  • The Science Behind Kratom: How It Works
    Kratom’s alkaloids interact with several key brain systems:

    Mu-opioid receptors – These are the same receptors activated by pain medications like morphine. Kratom acts as a partial agonist, offering pain relief and calm without full opioid side effects.
    Serotonin and dopamine receptors – Help improve mood, motivation, and reduce anxiety.
    Adrenergic receptors – Support energy and alertness, much like caffeine.
    One fascinating fact: 7-OH is about 10 times more powerful at pain relief than mitragynine, and in lab studies, it even outperformed morphine in mice—without causing heavy sedation or dangerous breathing issues.

  • Key Benefits of Kratom and 7-OH

    1. Pain Relief

    Kratom is widely used for managing chronic pain, arthritis, migraines, and more.
    7-OH binds powerfully to pain receptors—helping ease discomfort naturally.
    Users often find kratom provides similar relief to prescription painkillers but with fewer side effects.

    2. Mood Support & Mild Euphoria

    Acts on serotonin and dopamine systems to lift mood.
    Provides a sense of well-being and lightness.
    Can enhance sociability and motivation.

    3. Anxiety Reduction

    Many users report feeling more relaxed and less tense.
    Higher doses promote calm and mental stillness.
    Acts like a natural anti-anxiety tool—without prescription drugs.

    4. Energy & Focus

    At lower doses, kratom acts as a gentle stimulant.
    Boosts mental clarity, focus, and physical energy.
    Traditionally used by Southeast Asian workers for stamina.

    5. Opioid Withdrawal Support

    Kratom helps reduce symptoms like nausea, insomnia, and cravings.
    Used by many to taper off opioids naturally.
    Functions similarly to medications like Suboxone, but from a plant.

  • How It Differs from Opioids 

    ratom and 7-OH activate some of the same receptors as opioids—but in a gentler, more selective way. They’re known as “G-protein-biased agonists,” meaning they deliver pain relief and calm without strongly triggering the side effects that make opioids dangerous (like respiratory depression).

    In other words, kratom can relieve pain and anxiety without knocking you out or slowing your breathing like traditional opioids.

  • Coffee’s Wild Cousin

    Kratom comes from the same plant family as coffee, which may explain why small doses can offer a smooth energy boost, better focus, and even appetite control. Many users describe kratom as “calming yet uplifting”—a unique balance of stimulation and relaxation, depending on the dose.

  • Final Thoughts

    At Platte Hemp Company, we believe in the mindful and respectful use of natural wellness products. As with any supplement or botanical, kratom and its active compounds should be used responsibly and in moderation. Individual experiences may vary, and effects can depend on many factors including dosage, frequency, and individual health. Abuse or excessive use of any substance—natural or otherwise—can lead to unwanted effects. Please use with care, intention, and balance.

Try CBN Products at Platte Hemp Company

At Platte Hemp Company, we’re proud to offer a variety of CBN-infused products, including oils, gummies, and sleep blends. Whether you’re struggling with sleepless nights, aches and pains, or just looking to relax, CBN might be your new go-to cannabinoid.

Stop by one of our locations in Casper, Sheridan, or Gillette—or shop online—and talk to our team about how CBN can help you recharge naturally.

References

  • Boyer, E. W., Babu, K. M., Adkins, J. E., McCurdy, C. R., & Halpern, J. H. (2008). Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth). Addiction, 103(6), 1048–1050. https://doi.org/10.1111/j.1360-0443.2008.02209.x

  • Grundmann, O. (2017). Patterns of kratom use and health impact in the US—Results from an online survey. Drug and Alcohol Dependence, 176, 63–70. https://doi.org/10.1016/j.drugalcdep.2017.03.007

  • Hemby, S. E., McIntosh, S., Leon, F., Cutler, S. J., & McCurdy, C. R. (2019). Abuse liability and therapeutic potential of the kratom alkaloids mitragynine and 7-hydroxymitragynine. Addiction Biology, 24(5), 874–885. https://doi.org/10.1111/adb.12639

  • Kruegel, A. C., & Grundmann, O. (2018). The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse. Neuropharmacology, 134, 108–120. https://doi.org/10.1016/j.neuropharm.2017.08.026

  • Matsumoto, K., Horie, S., Ishikawa, H., Takayama, H., Aimi, N., & Watanabe, K. (2004). Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa. Life Sciences, 74(17), 2143–2155. https://doi.org/10.1016/j.lfs.2003.09.047

  • Swogger, M. T., & Walsh, Z. (2018). Kratom use and mental health: A systematic review. Drug and Alcohol Dependence, 183, 134–140. https://doi.org/10.1016/j.drugalcdep.2017.10.012

  • Veltri, C. A., & Grundmann, O. (2019). Current perspectives on the impact of kratom use. Substance Abuse and Rehabilitation, 10, 23–31. https://doi.org/10.2147/SAR.S179639

Please note: The legal landscape is continually evolving. For the most current information, consult legal experts or official state resources.